研究方向 有机超分子材料化学，研究工作以分子设计合成为基础，以分子识别与超分子可控组装为手段，以有机功能材料构筑为导向，旨在实现系列新型“智能”有机超分子组装体系的可控构筑及其功能调控。
学习工作经历 2011年6月，博士毕业于中科院成都生物所，药物化学； 2011年7月-2013年6月，南京大学博士后； 2013年7月-2016年6月，南京大学副研究员； 2016年7月-2018年6月，德国杜伊斯堡-埃森大学，洪堡资深学者（Humboldt Fellowship for Experienced Researcher）； 2018年7月-2024年8月，南京航空航天大学教授、长空学者； 2024年9月起，江西师范大学教授。
代表性论文或专利 1.M. Zuo, Y. Xie, R. Han, J. Jiao, K. Wang, L. Wang, X.-Y. Hu.* Adaptive co-crystals with switchable host-guest stoichiometry for dynamic regulation of photoluminescence. Adv. Mater., 2026, 38, e14110. 2.P. Jeyakkumar, K. Du, R. Zhang, X. Tian, Q. Liu, J. Jiao, H. Jiang,* X. Yu, X.-Y. Hu.* Pillararene-based AIE-active metallacycle for effective inhibition of antibiotic-resistant bacteria. Sci. China Chem., 2026, 69, 826-832. 3.X. Tian, C. Wang, T. Hu, X.-Y. Hu.* Macrocyclic hosts featuring a tetraphenylethene-embedded skeleton: from molecular design and photophysical properties to applications. Aggregate, 2025, 6, e70179. 4.R. Zhang, X. Tian, M. Zuo, T. Zhang, S. Pangannaya, X.-Y. Hu.* Bionic artificial leaves based on AIE-active supramolecular hydrogel for efficient photocatalysis. Adv. Sci.,2025, 64, 2504993. 5.X. Tian#, M. Zuo#, Y. Shen, N. Mao, K. Wang, Y. Sheng, K. Velmurugan, J. Jiao, X.-Y. Hu.* TPE-embedded butterfly bis-crown ether with controllable conformation and supramolecular chiroptical property. Nat. Commun., 2024, 15, 7182. 6.M. Zuo, T. Li, H. Feng, K. Wang, Y. Zhao, L. Wang, X.-Y. Hu.* Chaperone mimetic strategy for achieving organic room-temperature phosphorescence based on confined supramolecular assembly, Small, 2024, 19, 2306746. 7.Y.-Y. Liu, X.-Y. Yu, Y.-C. Pan, H. Yin, S. Chao, Y. Li, H. Ma, M. Zuo, K.-X. Teng, J.-L. Hou, Y. Chen, D.-S. Guo, R. Wang*, Y. Pei*, Z. Pei*, J.-F. Xu*, X.-Y. Hu*, C. Li*, Q.-Z. Yang*, L. Wang, Y. Liu*, Z.-T. Li*. Supramolecular systems for bioapplications: recent research progress in China. Sci. China Chem., 2024, 67, 1397-1441. 8.K. Wang, R. Zhang, Z. Song, K. Zhang, X. Tian, S. Pangannaya, M. Zuo, X.-Y. Hu.* Dimeric pillar[5]arene as a novel fluorescent host for controllable fabrication of supramolecular assemblies and their photocatalytic applications, Adv. Sci., 2023, 202206897. 9.X. Tian, S. Li, K. Velmurugan, Z. Bai, Q. Liu, K. Wang, M. Zuo,* X.-Y. Hu.*Photoswitchable AIE-active supramolecular photosensitizer with synergistic enhancement of ROS-generation ability based on two-step sequential FRET process, Mater. Chem. Front., 2023, 7, 2484. 10.K. Wang, Y. Shen, P. Jeyakkumar, Y. Zhang, L. Chu, R. Zhang, X.-Y. Hu.* Supramolecular artificial light-harvesting systems for photocatalysis, Curr. Opin. Green. Sust., 2023, 41, 100823. 11.K. Wang, M. Zuo, T. Zhang, H. Yue, X.-Y. Hu.* Pillar[5]arene–modified peptide-guanidiniocarbonylpyrrol amphiphiles with gene transfection properties, Chinese Chem. Lett., 2023, 34, 107848. 12.K. Velmurugan, A. Murtaza, A. Saeed, J. Li, K. Wang, M. Zuo, K. Zhang, X. Tian, Q. Liu, Z. Bai, X.-Y. Hu.*Supramolecular nanohelix fabricated by pillararene-based host-guest system for chirality amplification, transfer and circularly polarized luminescence in water. CCS Chem., 2022, 4, 3426-3439. 13.M. Zuo, W. Qian, K. Wang, L. Wang, X.-Y. Hu.* A novel supramolecular self-assembling hybrid system for visible-light-driven overall water splitting, Mater. Chem. Front., 2022, 6, 2790-2795. 14.K. Wang, X. Tian, J. H. Jordan, K. Velmurugan, L. Wang, X.-Y. Hu.* The emerging applications of pillararene architectures in supramolecular catalysis, Chinese Chem. Lett, 2022, 33, 89-96. 15.K. Wang, J. H. Jordan,K. Velmurugan, X. Tian, M. Zuo, X.-Y. Hu*, L. Wang. Role of functionalized pillararene architectures in supramolecular catalysis. Angew. Chem. Int. Ed.,2021, 60, 9205-9214. 16.X. Tian, M. Zuo, P. Niu, K. Velmurugan, K. Wang, Y. Zhao, L. Wang, X.-Y. Hu.* Orthogonal design of a water-soluble meso-tetraphenylethene-functionalized pillar[5]arene with aggregation-induced emission property and its therapeutic application. ACS Appl. Mater. Interfaces,2021, 13, 37466-37474. 17.G. Sun, M. Zuo, W. Qian, J. Jiao, X.-Y. Hu,* L. Wang.* Highly efficient artificial light-harvesting systems constructed in aqueous solution for supramolecular photocatalysis, Green Synth. & Catal., 2021, 2, 32-37. 18.K. Wang, J. H. Jordan, X.-Y. Hu*, L. Wang. Supramolecular strategies for controlling reactivity within confined nanospaces. Angew. Chem. Int. Ed.,2020, 59, 13712-13721. 19.G. Sun, W. Qian, J. Jiao, T. Han, Y. Shi, X.-Y. Hu*, L. Wang*. Highly efficient artificial light-harvesting system with two-step sequential energy transfer based on supramolecular self-assembly. J. Mater. Chem. A,2020, 8, 9590-9596. 20.X.-Y. Hu,K. Wang, J. H. Jordan,C. Su,L. Wang. General Strategies in Modulating Reactivity within Well-Defined Supramolecular Nanospaces, Supramolecular Catalysts, Leyong Wang and Chengyong Su, World Scientific Publishing, pp 1-27, Singapore, 2020. 21.M. Hao, G. Sun, M. Zuo, Z. Xu, Y. Chen, X.-Y. Hu*, L. Wang*. A supramolecular artificial light-harvesting system with two-step sequential energy transfer for photochemical catalysis. Angew. Chem. Int. Ed., 2020, 59, 10095-10100. 22.X. Liu, K. Wang, M. Externbrink, J. Niemeyer, M. Giese,X.-Y. Hu.* Control of secondary structure and morphology of peptide–guanidiniocarbonylpyrrole conjugates by variation of the chain length. Chinese Chem. Lett, 2020, 31, 1239-1242. 23.S. Wang, W. Gao, X.-Y. Hu,* Y.-Z. Shen, L. Wang. Supramolecular strategy for smart windows. Chem. Commun., 2019, 55, 4137-4149. 24.S. Guo, Y. Song, Y. He,X.-Y. Hu*, L. Wang*. Highly efficient artificial light-harvesting systems constructed in aqueous solution based on supramolecular self-assembly, Angew. Chem. Int. Ed., 2018, 57, 3163-3167. 25.S. Wang, Z. Xu, T. Wang, T. Xiao, X.-Y. Hu*, Y.-Z. Shen*, L. Wang*. Warm/cool-tone switchable thermochromic material for smart windows by orthogonally integrating properties of pillar[6]arene and ferrocene. Nat. Commun., 2018,9,1737. 26.X.-Y. Hu*, L. Gao, S. Mosel, M. Ehlers, E. Zellermann, H. Jiang, S. K. Knauer, L. Wang, C. Schmuck.* From supramolecular vesicles to micelles: Controllable construction of tumor-targeting nanocarriers based on host–guest interaction between a pillar[5]arene-based prodrug and a RGD-sulfonate guest. Small,2018, 14, 1803952. 27.M. Zuo, W. Qian, Z. Xu, W. Shao, X.-Y. Hu*, D. Zhang*, J. Jiang*, X. Sun, and L. Wang*. Multi-responsive supramolecular theranostic nanoplatform based on pillararene and diphenylboronic acid derivatives for integrated glucose sensing and insulin delivery, Small, 2018, 14, 1801942. 28.X.-Y. Hu, X. Liu, W. Zhang, S. Qin, C. Yao, Y. Li, D. Cao, L. Peng, L. Wang.* Controllable construction of biocompatible supramolecular micelles and vesicles by water-soluble phosphate pillar[5,6]arenes for selective anti-cancer drug delivery, Chem. Mater., 2016, 28, 3778-3788. 29.Y. Cao, Y. Li, X.-Y. Hu,* X. Zou,S. Xiong, C. Lin, L. Wang.* Supramolecular nanoparticles constructed by DOX-based prodrug with water soluble pillar[6]arene for self-catalyzed rapid drug release, Chem. Mater., 2015, 27, 1110-1119. 30.X.-Y. Hu, T. Xiao, C. Lin, F. Huang, L. Wang*. Dynamic supramolecular complexes constructed by orthogonal self-assembly, Acc. Chem. Res., 2014, 47, 2041-2051.
获奖情况 入选教育部高层次青年人才（2024年） 入选全球前2%顶尖科学家榜单（2024年） 德国“洪堡资深学者”（2016-2018年） 江苏省“333工程”高层次人才（2022年） “Vebleo Fellow Award”（2022年） 全国大环芳烃超分子化学学术新星奖（2020年） 江苏省科学技术奖一等奖（2019年） 江苏省教育教学与研究成果奖三等奖（2018年） Aggregate新锐科学家（2025年） Materials Chemistry Frontiers新锐科学家（2022年） “Chinese Chemical Letters”期刊杰出青年编委（2019年）
主持科研项目 1）国家自然科学基金面上项目，2026-2029； 2）国家自然科学基金面上项目，2023-2026； 3）国家自然科学基金中德合作与交流项目，2021-2025； 4）国家自然科学基金面上项目，2016-2019； 5）国家自然科学基金青年项目，2013-2015； 6）江西省自然科学基金重点项目，2025-2028； 7）江西省国家级人才创新项目，2025-2027； 8）江苏省自然科学基金杰出青年基金项目，2024-2027； 9）江苏省自然科学基金优秀青年基金项目，2018-2021； 10）江苏省自然科学基金面上项目，2021-2024； 11）江苏省港澳台科技合作项目，2023-2026； 12）江苏省自然科学基金青年项目，2015-2017；
学术任职 中国化学会超分子专业委员会委员； 江苏省化学化工学会大环与超分子专业委员会主任委员； 江苏省化学化工学会理事； 青海省藏药重点实验室学术委员会副主任； International Union of Pure and Applied Chemistry（IUPAC）委员会有机与生物分子化学分会国家代表； “Frontiers in Chemistry”副主编； “Current Opinion in Green and Sustainable Chemistry”客座副主编； “Chinese Chemical Letters”高级编委； “Green Synthesis & Catalysis”、“Journal of Inclusion Phenomena and Macrocyclic Chemistry”、“RSC Advance”及“Molecules”编委； Science、Nature等顶刊评审专家。
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