万结平
发布时间:2016-10-27 浏览次数:

 

 

 

更多最新信息参见我们课题组网站(随时更新)     

               http://www.escience.cn/people/wangroup/index.html

研究方向:有机合成,药物合成

联系方式wanjieping@126.com; wanjieping@jxnu.edu.cn

简介:

万结平,男,副教授,低职高聘教授。硕士生导师,2004年南昌大学本科毕业,2005年至2010年在浙江大学化学系潘远江教授课题组攻读博士研究生,20106月获理学博士学位。主要从事高效合成方法学以及生物活性有机小分子合成方面的研究,包括多组分合成以及过渡金属催化等。在国际知名期刊Journal of American Chemical Society, Organic Letters, Chemical Communications, Journal of Organic Chemistry, Chemistry-an Asian Journal, Green Chemistry, ChemCatChem等发表研究论文80余篇。主要获得荣誉和奖励有:Thieme Chemistry Journal Award 2014;江西省杰出青年基金;浙江省优秀毕业生;浙江大学优秀毕业生;浙江大学三好研究生;赢创奖学金(德国赢创-德固赛集团)等。20107月进入江西师范大学化学化工学院工作,独立工作以来已发表或接SCI收论文60余篇,被引用近1000次。20119月到20128月在德国亚琛工业大学有机化学研究所Dieter Enders教授课题组进行博士后研究。主持(含以完成)国家自然科学基金2项,江西省自然科学基金青年重大项目1项,江西省自然科学基金2项,江西省教育厅科技项目1项。2012年获江西师范大学首批青年英才计划项目。受邀担任Chemical Reviews, Green Chemistry, Chemical Communications, Chemistry-A European Journal, Journal of Organic Chemistry, Organic Chemistry Frontiers, RSC Advances, Tetrahedron, Synthesis, Synlett, Current Organic Chemistry, Synthetic Communications, Mini-review in Organic Chemistry, Chinese Journal of Chemistry, ChemistryOpen, 《化学通报》等多十余个国际化学期刊审稿人。

欢迎有志于从事有机合成研究的研究生和本科生同学加入课题组工作、学习!

 

主持在研项目:

国家自然科学基金地区基金          (no. 21562025)

国家自然科学基金青年基金          (no. 21102059)

中德科学中心林岛青年学者计划      (no. GZ710,合作导师Dieter Enders教授)

江西省自然科学基金青年基金        (no. 20114BAB213005)

浙江中医药大学基础医学院中药化学研究开放基金  (2015.01-2016.12)

江西省教育厅基金                              (GJJ13245)

江西师范大学青年英才计划项目(首批入选)         (2012.01-2014.12)

江西师范大学博士启动基金                              

江西师范大学青年基金                                  

 

代表性论文

最新论文发表情况,参见:

http://www.escience.cn/people/wangroup/paper.dhome

 

[1] Shanshan Zhong, Yunyun Liu, Xiaoji Cao, Jie-Ping Wan.* KIO3-catalyzed domino C(sp2)-H bond sulfenylation and C-N bond oxygenation of enaminones toward the synthesis of 3-sulfenylated chromones. ChemCatChem 2016, in press, DOI: 10.1002/cctc.201601273.

[2] Jie-Ping Wan,* Yanfeng Jing, Changfeng Hu, Shouri Sheng.* Metal-free synthesis of fully substituted pyridines via ring construction based on the domino reactions of enaminones and aldehydes. Journal of Organic Chemistry 2016, 81, 6826-6831.

[3] Jie-Ping Wan,* Yong Gao, Li Wei.* Recent advances in transition-metal-free oxygenation of alkene C=C double bonds for carbonyl generation. Chemistry-An Asian Journal 2016, 11, 2092-2102. (invited review)

[4] Jie-Ping Wan,* Yong Gao. Domino reactions based on combinatorial bond transformations in electron-deficient tertiary enamines. The Chemical Record 2016, 16, 1164-1177. (invited personal account)

[5] Yunyun Liu, Bin Huang, Xiaoji Cao, Jie-Ping Wan.* Tunable di- and mono-γ-C−H arylation of phenylacetamides by palladium-catalyzed domino reactions. ChemCatChem 2016, 8, 1470-1473.

[6] Jie-Ping Wan, Yi Li, Yunyun Liu.* Annulation based on 8-aminoquinoline assisted C–H activation: an emerging tool in N-heterocycle construction. Organic Chemistry Frontiers 2016, 3, 768-772.

[7] Jie-Ping Wan,* Shanshan Zhong, Lili Xie, Xiaoji Cao, Yunyun Liu, Li Wei. KIO3-catalyzed aerobic cross-coupling reactions of enaminones and thiophenols: synthesis of polyfunctionalized alkenes by metal-free C–H sulfenylation. Organic Letters 2016, 18, 584-587.

[8] Jie-Ping Wan,* Yunfang Lin, Xiaoji Cao, Yunyun Liu, Li Wei. Copper-catalyzed, hypervalent iodine mediated C=C bond activation of enaminones for the synthesis of α-keto amides. Chemical Communications 2016, 52, 1270-1273. (Web of Science 高被引论文).

[9] Jie-Ping Wan,* Youyi Zhou, Yunyun Liu, Shouri Sheng.* Metal-free oxidative carbonylation on enaminone C=C bond for the cascade synthesis of benzothiazole-containing vicinal diketones. Green Chemistry 2016, 18, 402-405.

[10] Jie-Ping Wan,* Shuo Cao, Yunyun Liu. A metal- and azide-free multicomponent assembly toward regioselective construction of 1,5-disubstituted 1,2,3-triazoles. Journal of Organic Chemistry 2015, 80, 9028-9033.

[11] Shuo Cao, Shanshan Zhong, Luoting Xin, Jie-Ping Wan,* Chengping Wen.* Visible-light-induced C=C bond cleavage of enaminones for the synthesis of 1,2-diketones and quinoxalines in sustainable medium. ChemCatChem 2015, 7, 1478-1482.

[12] Jie-Ping Wan,* Deqing Hu, Yunyun Liu, Shouri Sheng.* Azide-free synthesis of 1,2,3-triazoles: new opportunity for sustainable synthesis. ChemCatChem 2015, 7, 901-903.

[13] Jie-Ping Wan,* Hang Wang, Yunyun Liu, Hanfeng Ding.* Synthesis of 2-vinylbenzofurans via the copper-catalyzed multicomponent reactions involving an oxa-Michael/arylation/vinylation cascade. Organic Letters 2014, 16, 5160-5163.

[14] Jie-Ping Wan,* Yunfang Lin, Qing Huang, Yunyun Liu. Diastereoselective construction of tetrahydropyridine fused bicyclic structures via three-component domino Reaction. Journal of Organic Chemistry, 2014, 79, 7232-7238.

[15] Jie-Ping Wan,* Youyi Zhou, Shuo Cao. Domino reactions involving the branched C-N and C=C cleavage of enaminones toward pyridines synthesis. Journal of Organic Chemistry 2014, 79, 9872-9877.

[16] Yunyun Liu,* Hang Wang, Jie-Ping Wan.* Copper-catalyzed, C–C coupling-based one-pot tandem reactions for the synthesis of benzofurans using o-iodophenols, acyl chlorides, and phosphorus ylides. Journal of Organic Chemistry 2014, 79, 10599-10604.

[17] Yunyun Liu, Hang Wang, Jie-Ping Wan,*. Recent advances in diversity oriented synthesis through isatin-based multicomponent reactions. Asian Journal of Organic Chemistry, 2013, 2, 374-386.

[18] Yunyun Liu, Jie-Ping Wan*. Advances in copper-catalyzed c–c coupling reactions and related domino reactions based on active methylene compounds. Chemistry-An Asian Journal, 2012, 7, 1488-1501.

[19] Jie-Ping Wan, Charles C. J. Loh, Fangfang Pan, Dieter Enders.* Enantioselective orgnanocatalytic domino synthesis of tetrahydropyridin-2-ols. Chemical Communications 2012, 48, 10049-10051.

[20] Yunyun Liu,* Jie-Ping Wan. Tandem reactions initiated by copper-catalyzed cross-coupling: a new strategy towards heterocycle synthesis. Organic & Biomolecular Chemistry 2011, 9, 6873-6894.

[21] Runsheng Xu, Jie-Ping Wan, Hui Mao, Yuanjiang Pan*. Facile synthesis of 2-(phenylthio)phenols by copper(i)-catalyzed tandem transformation of C-S coupling/C-H functionalization. Journal of the American Chemical Society, 2010, 132, 15531-15533.

() 参加工作前(研究生时期)论文:

[1] Jie-Ping Wan, Yuan-Jiang Pan*. Chemo-/Regioselective Synthesis of 6-Unsubstituted Dihydropyrimidinones, 1,3-Thiazines and Chromones via Novel Variants of Biginelli Reaction. Chemical Communications 2009, 2768-2770.

[2] Jie-Ping Wan, Shi-Feng Gan, Gong-Lei Sun, Yuan-Jiang Pan*. Novel Regioselectivity: Three-component Cascade Synthesis of Unsymmetrical 1,4- and 1,2-Dihydropyridines. Journal of Organic Chemistry 2009, 74, 2862-2865.

[3] Jie-Ping Wan, Shi-Feng Gan, Jian-Mei Wu, Yuanjiang Pan*. Water Mediated Chemoselective Synthesis of 1,2-Disubstituted Benzimidazoles using o-Phenylenediamine and the Extended Synthesis of Quinoxalines. Green Chemistry 2009, 11, 1633-1637.

[4] Jie-Ping Wan, Jing Zhou, Hui Mao, Yuan-Jiang Pan*, An-Xin Wu. A New Diastereoselective Multicomponent, One-pot Strategy for the Synthesis of 3-Substituted Isoindolinones via Efficient C–C Bond Formation. Tetrahedron 2008, 64, 11115-11123.

[5] Jieping Wan, Bin Wu, Yuanjiang Pan*. Novel One-step Synthesis of 2-Carbonyl/Thiocarbonyl Isoindolinones and Mechanistic Disclosure on the Rearrangement Reaction of o-Phthalaldehyde with Smide/Thioamide Analogs. Tetrahedron, 2007, 63, 9338-9344.

[6] Jie-Ping Wan, Yun-Feng Chai, Jian-Mei Wu, Yuan-Jiang Pan*. N,N'-(Phenylmethylene)diacetamide Analogues as Economical and Efficient Ligands in Copper-Catalyzed Arylation of Aromatic Nitrogen-containing Heterocycles. Synlett, 2008, 3068-3072.

[7] Jie-Ping Wan, Yuan-Hang Pan, Hui Mao, Yun-Hua Chen, Yuan-Jiang Pan*. Microwave Assisted Three-component Reaction for Rapid Synthesis of Some 5,6-Dihydro-4H-1,3-thiazine Derivatives Under Solvent-Free Condition. Synthetic Communications, 2010, 40, 709-716.

[8] Chunyan Wang, Jieping Wan, Zhiguo Zheng, Yuanjiang Pan*. A New InCl3-Catalyzed Reduction of Anthrones and Anthraquinones by Using Aluminum Powder in Aqueous media. Tetrahedron, 2007, 63, 5071-5075.

[9] Hui Mao, Jieping Wan, Yuanjiang Pan*. Facile and Diastereoselective Synthesis of β-Acetamido Ketones and Keto Esters via Direct Mannich-type Reaction. Tetrahedron, 2009, 65, 1026-1032.

[10] Hui Mao, Jie-Ping Wan, Yuanjiang Pan*. Synthesis of 2-Substituted Indoles via a Palladium-Catalyzed Domino Heck Reaction and Dealkylation. Tetrahedron Letters, 2010, 51, 1844-1846.

[11] Shi-Feng Gan, Jie-Ping Wan, Yuan-Jiang Pan, Cui-Rong Sun*. Water-Mediated Multicomponent Reaction: A Facile and Efficient Synthesis of Multisubstituted Thiazolidine-2-thiones. Synlett, 2010, 973-975.

[12] Yunhua Chen, Jieping Wan, Chunyan Wang, Cuirong Sun*. Diastereoselective Synthesis of Cyclopentanediols by InCl3/Al Mediated Intramolecular Pinacol Coupling Reaction in Aqueous Media. Molecules, 2008, 13, 2652-2658.

[13] Jianmei Wu, Jieping Wan, Cuirong Sun*. Crystal Structure and Mass Spectrometric Fragmentation Behavior of Eprosartan. Chinese Journal of Structural Chemistry, 2009, 28, 1087-1092.

[14] Yulin Zhu, Shenlin Huang, Jieping Wan, Lei Yan, Yuanjiang Pan, Anxin Wu. Two Novel Diastereoselective Three-component Reactions of Alkenes or 3,4-Dihydro-(2H)-pyran with Urea/Tthiourea-Aldehyde Mixtures: [4+2] Cycloaddition vs Biginelli-Type Reaction. Organic Letters, 2006, 8, 2599-2602.

[15] Yunfeng Chai, Hezhi Sun, Jieping Wan, Yuanjiang Pan, Cuirong Sun. Hydride

Abstraction in Positive-ion Electrospray Interface: Oxidation of 1,4-Dihydropyridines in Electrospray Ionization Mass Spectrometry. Analyst, 2011, 136, 4667-4669.

[16] Yaqin Liu, Lihui Zhang, Jieping Wan, Yesen Li, Yuhong Xu, Yuanjiang Pan. Design and Synthesis of Cyclo[-Arg-Gly-Asp-Ψ(triazole)-Gly-Xaa-] Peptide Analogues by Click Chemistry. Tetrahedron, 2008, 64, 10728-10734.

[17] Cungui Cheng, Gonglei Sun, Jieping Wan, Cuirong Sun. Facile CuI-Catalyzed Arylation of Azoles and Amides Using Simple Enaminones as Efficient Ligands. Synlett, 2009, 2663-2668.

[18] Yuanpo Tai, Saifeng Pei, Jieping Wan, Xiaoji Cao, Yuanjiang Pan. Fragmentation study of protonated chalcones by atmospheric pressure chemical ionization and tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 2006, 20, 994-1000.

 

参编著作

Wan Jie-Ping, Multicomponent reactions 2, chapter 4 in Science of Synthesis. Ed: T. J. J. Müller, Georg Thieme Verlag KG. 2013, pp377-408.

 

学术报告

[1] 万结平于缺电子烯胺多样性转化模式的新合成方法研究。第十三届全国有机合成化学学术研讨会,邀请报告。扬州,201610.13-10.15

[2] 万结平基于缺电子烯胺的多样性合成:C−H转化到C=C转化。第九届全国有机化学化学会议,口头报告。长春,20157.28-7.31

[3] 万结平多组分反应研究中的一些新尝试。第八届全国有机化学化学会议,邀请报告。重庆,2013. 10.17-10.20

 

申请&授权专利

1. 万结平; 刘云云; 周友谊; 林云芳; 汪航。一种高效选择性合成β-烯氨酯和烯胺酮的方法。授权号:ZL 201210499533.X

2. 万结平;周友谊;刘云云。一种合成N,N-双取代烯胺酮类化合物的新方法。授权号:ZL 201410158357.2

3. 万结平,周友谊,刘云云。一种不对称的1.4-二氢吡啶化合物方法。申请号:201310418468.8.

4. 万结平,刘云云,张毅。一种邻碘苯甲腈的制备方法。ZL 201510237028.1.

 

 

 

信息最近更新时间:201611