万结平
发布时间:2018-01-11 浏览次数:

 

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               http://www.escience.cn/people/wangroup/index.html

研究方向:有机合成,药物合成

联系方式wanjieping@126.com; wanjieping@jxnu.edu.cn

简介:

万结平,男,教授。博士、硕士生导师2004年南昌大学本科毕业,2005年至2010年在浙江大学化学系攻读博士研究生,20106月获理学博士学位。受国家基金委中德科学基金资助,2011-2012年在德国亚琛工业大学从事合作研究。目前主要研究兴趣为多功能平台合成子(platform synthons)和实用试剂开发应用、多样性导向合成、环境友好型催化以及相关的有机化合物生物活性研究等。独立工作以来,已经发表专业领域学术论文80余篇,论文被引用1500余次,H-index20。作为第一完成人,获得国家发明专利授权5项。目前已经培养毕业硕士7名,所有毕业生毕业成绩均为双优(即论文评审和答辩成绩均为优秀)”,其中5/次获得过研究生国家奖学金,多人获得省/校级优秀论文。个人获得主要荣誉和奖励有:Thieme Chemistry Journal Award (2014)、江西省杰出青年基金、江西师范大学熊智明奖教金、江西师范大学“三育人”先进工作者、浙江省优秀毕业生、浙江大学优秀毕业生、浙江大学三好研究生、赢创奖学金(德国赢创-德固赛集团)等。主持(含已完成)国家自然科学基金2项,江西省自然科学基金青年重大项目1项,江西省自然科学基金2项,江西省教育厅科技项目2(含已获批重点项目1)2012年获江西师范大学首批青年英才计划项目。受邀担任Chemical Reviews, ACS Catalysis, Organic Letter, Green Chemistry, Chemical Communications, Chemistry-A European Journal, Journal of Organic Chemistry, Organic Chemistry Frontiers, Organic & Biomolecular Chemistry, New Journal of Chemistry, RSC Advances, Tetrahedron, European Journal of Organic Chemistry, Synthesis, Synlett, Current Organic Chemistry, Synthetic Communications, Mini-review in Organic Chemistry, Chinese Journal of Chemistry, ChemistryOpen, 《有机化学》,《化学通报》等多十余个国内国际化学期刊审稿人。

欢迎有志于从事有机合成研究的研究生和本科生同学加入课题组工作、学习!

 

主持科研项目:

国家自然科学基金地区基金          (no. 21562025)

国家自然科学基金青年基金          (no. 21102059,完成)

中德科学中心林岛青年学者计划      (no. GZ710,亚琛工大,完成)

江西省自然科学基金青年重大项目    (20161ACB21010)

江西省杰出青年基金                (20162BCB23023)

江西省自然科学基金面上项目        (20151BAB203008,完成)

江西省自然科学基金青年基金        (no. 20114BAB213005,完成)

浙江中医药大学基础医学院中药开放基金重点项目

江西省教育厅基金                              (GJJ13245,完成)

江西师范大学青年英才计划项目(首批入选)         (2012.01-2014.12,完成)

江西师范大学博士启动基金                              

江西师范大学青年基金                                  

 

工作以来发表的代表性论文 (最新及详细论文发表情况,参见课题组网站)

(25) Jie-Ping Wan,* Shanshan Zhong, Lili Xie, Xiaoji Cao, Yunyun Liu, Li Wei. KIO3-Catalyzed aerobic cross-coupling reactions of enaminones and thiophenols: synthesis of polyfunctionalized alkenes by metal-free C–H sulfenylation. Organic Letters 2016, 18, 584-587.

(24) Jie-Ping Wan,* Shuo Cao, Yunyun Liu. Base-promoted synthesis of n-substituted 1,2,3-triazoles via enaminone–azide cycloaddition involving Regitz diazo transfer. Organic Letters 2016, 18, 6034-6037.

(23) Jie-Ping Wan,* Hang Wang, Yunyun Liu, Hanfeng Ding.* Synthesis of 2-vinylbenzofurans via the copper-catalyzed multicomponent reactions involving an oxa-Michael/arylation/vinylation cascade. Organic Letters 2014, 16, 5160-5163.

(22) Jie-Ping Wan,* Yunfang Lin, Xiaoji Cao, Yunyun Liu, Li Wei. Copper-catalyzed, hypervalent iodine mediated C=C bond activation of enaminones for the synthesis of α-keto amides. Chemical Communications 2016, 52, 1270-1273.

(21) Jie-Ping Wan, Charles, C. J. Loh, Fangfang Pan, Dieter Enders.* Enantioselective organocatalytic domino synthesis of tetrahydropyridin-2-ols. Chemical Communications 2012, 48, 10499-10051.

(20) Jie-Ping Wan,* Youyi Zhou, Yunyun Liu, Shouri Sheng.* Metal-free oxidative carbonylation on enaminone C=C bond for the cascade synthesis of benzothiazole-containing vicinal diketones. Green Chemistry 2016, 18, 402-405.

(19) Yunyun Liu,* Yi Zhang, Jie-Ping Wan.* Multicomponent synthesis of diverse o-arylated benzamides via o-aminophenol (OAP) directed C(sp2)-H arylation. Journal of Organic Chemistry 2017, 82, 8950-8957.

(18) Jie-Ping Wan,* Yanfeng Jing, Changfeng Hu, Shouri Sheng.* Metal-free synthesis of fully substituted pyridines via ring construction based on the domino reactions of enaminones and aldehydes. Journal of Organic Chemistry 2016, 81, 6826-6831.

(17) Jie-Ping Wan,* Shuo Cao, Yunyun Liu. A Metal- and azide-free multicomponent assembly toward regioselective construction of 1,5-disubstituted 1,2,3-triazoles. Journal of Organic Chemistry 2015, 80, 9028-9033.

(16) Jie-Ping Wan,* Yunfang Lin, Qing Huang, Yunyun Liu. Diastereoselective construction of tetrahydropyridine fused bicyclic structures via three-component domino reaction. Journal of Organic Chemistry 2014, 79, 7232-7238.

(15) Jie-Ping Wan,* Youyi Zhou, Shuo Cao. Domino reactions involving the branched c–n and c═c cleavage of enaminones toward pyridines synthesis. Journal of Organic Chemistry 2014, 79, 9872-9877.

(14) Yunyun Liu,* Hang Wang, Jie-Ping Wan.* Copper-catalyzed, C–C coupling-based one-pot tandem reactions for the synthesis of benzofurans using o-iodophenols, acyl chlorides, and phosphorus ylides. Journal of Organic Chemistry 2014, 79, 10599-10604.

(13) Jie-Ping Wan, Yi Li, Yunyun Liu.* Annulation based on 8-aminoquinoline assisted C–H activation: an emerging tool in N-heterocycle construction. Organic Chemistry Frontiers 2016, 3, 768-772.

(12) Shanshan Zhong, Yunyun Liu, Xiaoji Cao, Jie-Ping Wan.* KIO3-catalyzed domino C(sp2)-H bond sulfenylation and C-N bond oxygenation of enaminones toward the synthesis of 3-sulfenylated chromones. ChemCatChem 2017, 9, 465-468.

(11) Yunyun Liu, Bin Huang, Xiaoji Cao, Jie-Ping Wan.* Tunable di- and mono-γ-C−H arylation of phenylacetamides by palladium-catalyzed domino reactions. ChemCatChem 2016, 8, 1470-1473.

(10) Shuo Cao, Shanshan Zhong, Luoting Xin, Jie-Ping Wan.* Chengping Wen.* Visible-Light-Induced C=C Bond Cleavage of Enaminones for the Synthesis of 1,2-Diketones and Quinoxalines in Sustainable Medium. ChemCatChem 2015, 7, 1478-1482.

(9) Jie-Ping Wan,* Deqing Hu, Yunyun Liu, Shouri Sheng.* Azide-Free Synthesis of 1,2,3-Triazoles: New Opportunity for Sustainable Synthesis. ChemCatChem 2015, 7, 901-903.

(8) Jie-Ping Wan,* Yong Gao, Li Wei.* Recent Advances in Transition-Metal-Free Oxygenation of Alkene C=C Double Bonds for Carbonyl Generation. Chemistry-An Asian Journal 2016, 11, 2092-2102.

(7) Yunyun Liu, Jie-Ping Wan*. Advances in copper-catalyzed C-C coupling reactions and related domino reactions based on active methylene compounds. Chemistry-An Asian Journal 2012, 7, 1488-1501.

(6) Jie-Ping Wan,* Yong Gao. Domino Reactions Based on Combinatorial Bond Transformations in Electron-Deficient Tertiary Enamines. The Chemical Record 2016, 16, 1164-1177.

(5) Yi Li, Xiaoji Cao, Yunyun Liu, Jie-Ping Wan.* Regioselective three-component synthesis of 2,3-disubstituted quinolines via the enaminone modified Povarov reaction. Organic & Biomolecular Chemistry 2017, 15, 9585-9589.

(4) Jie-Ping Wan,* Lu Gan, Yunyun Liu.* Transition metal-catalyzed C–H bond functionalization in multicomponent reactions: a tool toward molecular diversity. Organic & Biomolecular Chemistry 2017, 15, 9031-9043.

(3) Yong Gao, Li Wei, Yunyun Liu,* Jie-Ping Wan.* Iodine-mediated synthesis of sulfur-bridged enaminones and chromones via double C(sp2)–H thiolation. Organic & Biomolecular Chemistry 2017, 15, 4631-4634.

(2) Shanshan Zhong, Yu Lu, Yan Zhang, Yunyun Liu, Jie-Ping Wan.* Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones. Organic & Biomolecular Chemistry 2016, 14, 6270-6273.

(1) Jie-Ping Wan*, Chunping Wang, Yunyun Liu. Direct synthesis of enaminone functionalized biaryl ethers by CuI-catalyzed O-arylation of enaminone functionalized phenols. Organic & Biomolecular Chemistry 2011, 9, 6481-6483.

 

英文论著

(1) Wan Jie-Ping, chapter 4: Silicon mediated multicomponent reactions, in Multicomponent reactions 2, Science of Synthesis. Ed: T. J. J. Müller, Georg Thieme Verlag KG. 2013, pp377-408.

(2) Wan Jie-Ping, chapter 5: The application of acetone and acetate, in Solvents and Reagents in Organic Synthesis-Reactions and Applications. Ed. Xiao-Feng Wu, Wiley-VCH, 2017, pp161-197.

 

授权发明专利

(1) 万结平,周友谊,刘云云。一种多组分反应合成具有不对称结构1.4-二氢吡啶及其衍生物的方法。ZL 201310418468.8

(2) 万结平,周友谊,刘云云。一种合成N,N-双取代烯胺酮类化合物的新方法。ZL 201410158357.2

(3) 万结平,刘云云,周友谊,林云芳,汪航。一种高效选择性合成β-烯氨酯和烯胺酮的方法。ZL 201210499533.X

(4) 万结平,刘云云,张毅。一种邻碘苯甲腈的制备方法。ZL 201510237028.1

(5) 万结平,刘云云,张毅。一种基于硫粉合成噻蒽的方法。ZL 201510176702.X

 

学术会议报告

[1] 万结平C-H Elaboration of Enaminones By Cross-Coupling Transformation. 全国第十四届有机合成化学学术研讨会,口头报告。淮北,201710.26-10.29

[2] 万结平缺电子烯胺的多样性键官能化反应2017江南大学首届药物化学与有机合成学术论坛,邀请报告。无锡,20179.14-9.16

[3] Jie-Ping Wan. Enaminone as a platform in diversity oriented synthesis. The 12th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-12). One-minute Oral presentation. Xi’an, China. 2017, 1102-1105.

[4] 万结平于缺电子烯胺多样性转化模式的新合成方法研究。第十三届全国有机合成化学学术研讨会,邀请报告。扬州,201610.13-10.15

[5] 万结平基于缺电子烯胺的多样性合成:C−H转化到C=C转化。第九届全国有机化学化学会议,口头报告。长春,20157.28-7.31

[6] 万结平多组分反应研究中的一些新尝试。第八届全国有机化学化学会议,邀请报告。重庆,2013. 10.17-10.20

 

信息最近更新时间:20181